Atomic force microscopy for imaging human metaphase chromosomes
نویسندگان
چکیده
منابع مشابه
GTG banding pattern on human metaphase chromosomes revealed by high resolution atomic-force microscopy.
Surface topography of human metaphase chromosomes following GTG banding was examined using high resolution atomic force microscopy (AFM). Although using a completely different imaging mechanism, which is based on the mechanical interaction of a probe tip with the chromosome, the observed banding pattern is comparable to results from light microscopy and a karyotype of the AFM imaged metaphase s...
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Intermodulation atomic force microscopy (IMAFM) is a dynamic mode of atomic force microscopy (AFM) with two-tone excitation. The oscillating AFM cantilever in close proximity to a surface experiences the nonlinear tip-sample force which mixes the drive tones and generates new frequency components in the cantilever response known as intermodulation products (IMPs). We present a procedure for ext...
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Atomic force microscopy (AFM) has been used to image a variety of virus particles in vitro and could, conceivably, be used as a useful diagnostic for their presence, their structural characterization and even their identification. Virus particles can be imaged by AFM in air, under alcohol or in physiological medium, and accurate measurements of their dimensions obtained. In addition, the appear...
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ژورنال
عنوان ژورنال: Chromosome Research
سال: 2008
ISSN: 0967-3849,1573-6849
DOI: 10.1007/s10577-008-1241-7